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This is the result of increased expression of a number of proteins that are responsible for mitochondrial biogenesis, including peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), PGC-1β, mitochondrial transcription factor A (TFAM), and nuclear factor erythroid 2-related factor 2 (NRF2) 56,96

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Mol Med (Cambridge Mass)